Things to know about prevent aging problems. So is more of a concern when I found out that the essential hormones in the human body decrease in men and women from age 24. I became anxious, looking further into its causes and possibly preventing aging problems.
I found out that, there are profound changes in women, especially during Menopause. This has raised a lot of concerns in the few past years.
Researchers have come up to provide different help on things to know about prevent aging problems and other diseases that come with it.
The average life expectancy of a person around 1900 was 44 – 47 years. It has risen to around 79 years. Thanks to improved living conditions and medical progress.
The trend continues to rise. Chemical medicine only treats symptoms of old age diseases that have already occurred.
The aim of anti-aging medicine is to prevent chronic diseases. In a targeted manner or to mitigate or slow down age-related processes.
The Actions of Anti-Aging Medicine
Anti-aging medicine works on a three-basic principle. The first principle is about your lifestyle. It must be put to check and adjust if necessary.
That includes a balanced diet, enough exercise, and mental fitness training. It also includes recognizing personal risks when they occur.
The second principle helps the body.
Fight free radicals with matched vitamins, minerals, trace elements, and antioxidants.
These vital substances. Such as B, Resveratrol, or Coenzyme Q10 are also essential for the function of many enzymes. And it is building and maintaining all body structures.
Natural Hormones
Contrary to many prejudices. Hormone therapy is not about the extra administration of artificial hormones. But about substituting natural hormones.
The third principle of treatment is to supplement missing hormones (substitution).
The hormone substitution is supposed to compensate for exactly those hormones because the body no longer produces enough of itself.
Contrary to many prejudices. It is not about the extra administration of artificial hormones—quite the opposite: with a detailed examination.
You can determine which hormones are deficient. Only these need replacement.
The substitution takes place with natural hormones. Many people know this, e.g., B.
Thyroid hormone therapy. Not only are adjusted individual doses of natural hormones prescribed.
Estrogens and testosterone should go into the system as a gel through the skin. In contrast, some hormones have to be taken as tablets or capsules.
Usually, the following hormones are complete: DHEA, 5-HTP, estrogens, progesterone, testosterone, and melatonin.
Thanks to the correct form of application and the individual dosage. The quality of life for many people can have improved.
Above all, hormone replacement therapy counteracts osteoporosis, cardiovascular diseases, diabetes, and erectile dysfunction.
The Menopause of Women – Menopause, And Climacteric
They are compensating for the falling hormone level. Ensures that the natural balance of hormones is in place for better well-being during Menopause.
Most women in their mid-40s have what is known as climacteric. Gradually, the hormone production declines.
First, the progesterone (luteal hormone) drops, later, the estrogen. The duration and intensity of Menopause are very individual.
Around a third of women have severe physical and mental problems. A further third moderate to mild complaints, and a third have no difficulties.
Typical menopausal symptoms. Symptoms include hot flashes, sweats, sleep disturbances, fatigue, depression, palpitations, vaginal dryness, and muscle pain. And joint pain, urinary incontinence, and obesity.
Progesterone and estrogen fulfill extensive structural and protective functions in the body.
A long-term hormone deficiency, as it occurs during and after Menopause, thus has many negative consequences.
The elasticity of the muscles decreases, osteoporosis and arthrosis progress faster—the risk of hardening of the arteries, high blood pressure increases. And stroke adult-onset diabetes can develop, as there is a risk of senile dementia.
Diagnosing And Treating Menopausal Symptoms
Treatment always begins with a thorough measurement of the hormone levels. It is also essential to take the patient’s situation into account.
And to take a family history to identify and avoid possible risks of treatment at an early menopause sign. Only then is the hormone replacement determined.
Until recently, hormone therapy for menopausal symptoms prescribed excessive amounts of estrogen. It came in the form of tablets. Besides, artificial prostagestins were also prescribed.
In this form, hormone replacement led to many side effects. Such as biliary disease or thrombosis. And a slight increase in certain cancers – especially breast cancer.
Today we know that this is the wrong way to go. But, at this point, it must be put into perspective.
That being overweight and alcohol consumption, Increases the risk of cancer more than excessive and incorrect estrogens.
The correct approach is to compensate for the declining hormone levels. You can achieve this by restoring the natural balance between estrogen and progesterone.
The dosage form of the estrogen is also decisive:
Suppose the estrogen goes into the body as a gel through the skin. It can vary from individuals.
But, possible biliary diseases, a. If it cannot enter through the digestive tract. The second significant point is that natural progesterone is also supplemented (substituted).
The large trials on hormone therapy have demonstrated that. The inclusion of a synthetic progestogen increases the risk of breast cancer. This could not be observed for natural progesterone.
Besides, natural progesterone has mood-enhancing, anxiety-relieving, and sleep-promoting properties.
It has a dehydrating and antihypertensive effect which does not pose much risk of thrombosis.
One large study found that. Taking transdermal estrogen and natural progesterone did not increase the risk of cancer.
On our particular page, “Menopause,” we answer the most frequently asked questions about the causes, symptoms, and treatment options for menopausal symptoms in women.
Andropause – The Man’s Menopause
The decrease in the hormones DHEA and testosterone. Often leads to listlessness or libido and erectile dysfunction in men.
As we know today, men too “go through menopause.” This period of male hormonal changes is called andropause. Or climacteric virile (virile = male).
Older men often suffer from listlessness or libido and erectile dysfunction. These problems are accompanied by a drop in the hormones DHEA and testosterone.
In contrast to women, the decrease in hormones does not start at a specific moment. But it has taken place over the years.
This androgen deficit, i.e., the deficiency of male hormones, can lack vitality. In addition, stress intolerance, wilting of the skin, hair loss, anemia, and osteoporosis.
And results in a change in the relationship between body fat and muscle mass. The so-called “body composition.”
Estrogens also play a significant role in men, deficient estrogen levels. It can be partly responsible for men’s increased sweating, cardiovascular diseases, arteriosclerosis, osteoporosis, and erectile dysfunction.
Diagnosis And Treatment
First, the hormone levels are determined with a blood test. Next, a medical interview provides current complaints, previous illnesses, and lifestyles. Therapy consists in compensating for the hormone deficiency with natural hormones. Vitamins, minerals, or antioxidants can support the treatment.
What you can do yourself would help if you exercised. Movement stimulates metabolism and circulation. It slows down breakdown processes in the organism and prevents obesity.
A balanced diet that contains many fresh vegetables, lean meat, and fish. And low-fat dairy products are of great importance.
Make sure you drink enough water and unsweetened tea. Also, it would help if you avoided nicotine and too much alcohol.
Disturbed Day- Night Rhythm
Jet lag and shift work Jet lag is an endocrine, i.e., hormonal, the body’s reaction to a rapid change in time differences. The body’s functions follow a certain rhythm that is more or less the same every day. Melatonin and serotonin play one of the essential roles in this “internal clock.”
The “sleep hormone.” melatonin is released at night, ensuring restful sleep is an essential function as a rhythm generator. Its antagonist is serotonin, which removes, especially during the day, depending on the light.
Serotonin is necessary for our well-being. And, among other things, responsible for eating behavior. You can find more information about melatonin here.
Fascinating, nocturnal hormone. With jetlag and shift work, our day-night rhythm gets out of balance.
The consequence is, among other things, an acceleration of the aging process. A weakening of the immune system accompanies this—chronic states of exhaustion and weight gain (especially as belly fat).
The stress hormone cortisol increases. It has long been proven that the life expectancy of shift workers can be reduced due to the chronic disturbance in the melatonin-serotonin balance.
Melatonin deficiency can also lead to menstrual disorders in women as it reduces the secretion of the vital messenger substances LH and FSH in the brain.
We need to adapt the sleep times to the new time zone before a long-haul flight. If possible, you should not take any sleeping pills!
Taking melatonin to relieve jetlag has proven its worth. Preparations that release the active ingredient over a certain period work best.
Depending on the individual serotonin level. Taking the natural amino acid 5-hydroxytryptophan (5-HTP) can also be helpful.
Burnout syndrome. Burnout is a complex of symptoms that also occurs at a young age, but burnout occurs more in later years of life.
While it affects people in helping professions, such as doctors and teachers, burnout is widespread. Unfortunately, that can be found in all professional groups.
The experience can vary from person to person. For example, feeling down or depressed, but also physical complaints. Such as insomnia, headaches, stomach cramps, tinnitus, or digestive problems.
Knowing What Burnout Syndrome Is All About
Burnout syndrome describes a state of chronic exhaustion after a long phase of physical and mental overexertion.
In burnout syndrome, the hormones in the body are always out of balance. Above all, the production of melatonin, which controls sleep and circadian rhythms is inhibited.
There is also a drop in essential hormones. Such as estradiol, testosterone, cortisol, and DHEA.
Nutritional supplements with vitamins and minerals change life’s situation and reassess one’s performance.
Temporary substitution of natural hormones can provide outstanding support for the treatment and contribute to faster recovery.
Anti Aging Gene Therapy
The primary goal of anti-aging research is to extend one’s life expectancy. Innovative gene therapy-based techniques appear to be among the most promising for preventing and treating chronic polygenic illnesses, including age-related ones, at the moment.
Gene-based therapy allows for direct (e.g., by gene editing) and indirect (e.g., by viral or non-viral vectors) genome architecture modulation.
Nonetheless, given the remarkable complexity of the processes involved in aging and age-related disorders, the efficacy of these therapeutic choices is frequently inadequate and limited by their side effects.
Thus, clinical implementation of such applications will undoubtedly be a lengthy process requiring numerous translation phases to overcome problems.
However, once these issues are resolved, their application in clinical practice will undoubtedly open up new avenues in anti-aging treatment. Therefore, this section will evaluate and analyze recent advancements in this fast-evolving study subject.
A rising research volume reveals that aging is preventable with many treatment possibilities ranging from simple lifestyle changes to significant genetic interventions.
Scientists demonstrated in 2017 that utilizing medications to alter epigenetic markers. Chemical attachments are crucial for genome regulation. They improved the lifespan of mice by 30%.
George Church, a well-known geneticist, has even founded rejuvenate Bio, which offers anything from simple lifestyle adjustments to drastic genetic manipulations. With the attempts to lengthen the lives of dogs using patented genetic treatments.
He confesses that the ultimate goal is to apply his technique to humans.
Church’s team at Harvard also demonstrated that last month. Employing gene treatments was beneficial in managing three age-related illnesses in mice.
As a result, the first anti-aging treatments for people are being developed. A study recently published earlier this year shows that participants also demonstrated symptoms of a revitalized immune system. As a result, the FDA recently issued a public notice. Advising people to stop injecting blood plasma from minors.
The concept is based on recent research showing a rejuvenating impact in mice. But most experts believe that the anti-age therapy is far too early to apply to humans.
It is unclear if the FDA will keep up with this growing and profitable business. But given the possible adverse anti-aging medicine. Side effects of many of these medicines should be a top focus. We must also investigate what these longevity medicines signify for our culture.
Assuming the latest trials are successful. What does it mean? If only individuals with a million dollars to spare have the opportunity to live longer?
How will the treatment of anti-aging impact the character of our civilization? And our coexistence on earth if it becomes trivial?
These questions will become vital for us—for example, research and longevity firms, in the future decades.
Suppose the latest experiments are practical. Then, what does it mean if only people with a million dollars left have the option to live longer?
Disclaimer:
While we attempt to provide accurate, up-to-date, and safe information in all of our articles and guides, it’s important to note that they are not a replacement for medical advice from a doctor or healthcare practitioner. Whenever possible, you should consult a practicing professional who can diagnose your situation. This guide’s content is only informative and does not constitute medical advice.
Source:
https://www.researchgate.net/publication/337024966_A_single_combination_gene_therapy_treats_multiple_age-related_diseases
